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ZINC000081009201

ZINC000081009201 is a potent poly (ADP-ribose) polymerase 1 (PARP1) inhibitor with an IC50 value of 1.4767 μM. ZINC000081009201 is promising for research of triple-negative breast cancer (TNBC) [1].

Product Specifications

CAS Number

1424500-13-9

UNSPSC

12352005

Target

PARP

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Smiles

CN1C2=CC=CC=C2N=C1CCCNC3=NC4=CC=CC=C4C(N3)=O

Molecular Formula

C19H19N5O

Molecular Weight

333.39

References & Citations

[1]Polk S, et al. Discovery of PARP‐1 Inhibitors for Triple‐Negative Breast Cancer via Structure‐Based Virtual High‐Throughput Screening[J]. ChemistrySelect, 2025, 10 (24) : e00460.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PARP1

Frequently Asked Questions

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