HCA-I/hCA-II-IN-1
HCA-I/hCA-II-IN-1 (Compound P4) is a potent dual human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II) inhibitor with Ki values of 0.22 μM and 0.33 μM, respectively. hCA-I/hCA-II-IN-1 can be used in research on diseases related to CA enzymes such as glaucoma, hypertension, and ulcers[1].
Product Specifications
UNSPSC
12352100
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
CC1=C(C=C(C=C1)CCC(NC2=CC(S(N)(=O)=O)=CC=C2)=O)C
Molecular Formula
C17H20N2O3S
Molecular Weight
332.42
References & Citations
[1]Güneş F, et al. Synthesis and Carbonic Anhydrase Inhibition Profiles of N- (3-sulfamoylphenyl) propanamide/benzamide Derivatives: Experimental and Computational Insights With Absorption, Distribution, Metabolism, and Excretion Profiling. Chem Biodivers. 2025 May 27:e03435.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA I
Curated Selection
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