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MAO-A-IN-2

MAO-A-IN-2 (Compound 4l) is a selective monoamine oxidase A (MAO-A) inhibitor with an IC50 value of 0.4 μM. MAO-A-IN-2 reduces the degradation of monoamine neurotransmitters (e.g., serotonin, norepinephrine) . MAO-A-IN-2 is promising for research of neurological diseases related to monoamine neurotransmitter imbalance such as depression and anxiety disorders[1].

Product Specifications

CAS Number

[1627618-37-4]

UNSPSC

12352005

Target

Monoamine Oxidase

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(C1=C(NC2=CC=C(Cl)C=C2)CC(C3=CC=C([N+]([O-])=O)C=C3)N(C4=CC=C(Cl)C=C4)C1C5=CC=C([N+]([O-])=O)C=C5)OCC

Molecular Formula

C32H26Cl2N4O6

Molecular Weight

633.48

References & Citations

[1]Khan O R, et al. Design, Synthesis, Biological Evaluation, and In Silico Study of Tetrahydropyridines as Prospective Monoamine Oxidase Inhibitors[J]. ChemistryOpen, e202400516.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MAO-A

Curated Selection

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