PAK4-IN-6
PAK4-IN-6 is a selective degrader of PAK4. PAK4-IN-6 can be used to synthesize PROTACs such as CPS-021 (HY-174247) [1].
Product Specifications
CAS Number
[2755835-86-8]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; PAK
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; PROTAC
Field of Research
Others
Smiles
NC1=NC=CC(N2C=C(C3=CC=C(C=C32)C#CC4(CCCCC4)O)C(N5CCNCC5)=O)=N1
Molecular Formula
C25H28N6O2
Molecular Weight
444.53
References & Citations
[1]Hanxun Wang, et al., Design, Synthesis, and Biological Evaluation of Selective PAK4 Degrader for the Treatment of Lung Tumor Metastasis. J. Med. Chem. 2025, 68, 11, 11231–11269.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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