Jun15799
Jun15799 is an Enterovirus (EVs) 2C protein (EVs 2C) inhibitor with Kis of 0.8, 21.1 and 3.0 μM for EV-D68, EV-A71 and CVB3, respectively. Jun15799 has a significant antiviral activity against EV-D68 US/MO/14-18947, EV-A71 Tainan/4643/1998 and CVB3 Nancy cells (EC50s of 0.3, 11.4 and 0.3 μM, respectively) . Jun15799 can be used for viral infections research, such as meningitis, hand, foot and mouth disease (HFMD) and viral myocarditis[1].
Product Specifications
UNSPSC
12352005
Target
Enterovirus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=CC(C2=CC=CC=C2)=NC(C3=CC=CC=C3)=C1)NCCN(C)C
Molecular Formula
C22H23N3O
Molecular Weight
345.44
References & Citations
[1]Li K, Demssie HA, et al. Design of a Fluorescence Polarization Probe for Enterovirus 2C Proteins. J Med Chem. 2025 Jul 10;68 (13) :14041-14053.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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