Jun15716
Jun15716 is an Enterovirus (EVs) 2C protein (EVs 2C) inhibitor with Kis of 15.9, 44.2 and 17.8 μM for EV-D68, EV-A71 and CVB3, respectively. Jun15716 has a potent antiviral activity against EV-D68 US/MO/14-18947 and CVB3 Nancy cells (EC50s of 1.0 and 0.7 μM, respectively) . Jun15716 can be used for viral infections research, such as meningitis, hand, foot and mouth disease (HFMD) and viral myocarditis[1].
Product Specifications
CAS Number
[827034-42-4]
UNSPSC
12352005
Target
Enterovirus
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)NCCN(C)C
Molecular Formula
C19H32N2O
Molecular Weight
304.47
References & Citations
[1]Li K, Demssie HA, et al. Design of a Fluorescence Polarization Probe for Enterovirus 2C Proteins. J Med Chem. 2025 Jul 10;68 (13) :14041-14053.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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