Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-Cl
Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-Cl is a cleavable and silyl ether-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADC) [1].
Product Specifications
UNSPSC
12352005
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
C=CS(=O)(N1CCN(C[C@H]1C(NCC2=CN(N=N2)CCOCCOCCOCCO[Si](C(C)C)(C(C)C)Cl)=O)S(=O)(C=C)=O)=O
Molecular Formula
C26H47ClN6O9S2Si
Molecular Weight
715.35
References & Citations
[1]Wang H, et al. Triptolide-based cleavable antibody-drug conjugates for pancreatic cancer. Eur J Med Chem. 2025 Oct 5;295:117798.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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