HSP90i-COCH2CH2-PEG4-NHBoc
HSP90i-COCH2CH2-PEG4-NHBoc is a conjugate of the HSP90 Ligand and the linker (HY-W021787). HSP90i-COCH2CH2-PEG4-NHBoc can be used for synthesis of LYTACs, such as dPDL1-4 (HY-174468).
Product Specifications
UNSPSC
12352005
Target
HSP
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
CC(C1=C(C=C(C(C2=NN=C(N2C3=CC=C(C=C3)CN4CCN(CC4)C(CCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O)O)=C1)O)O)C
Molecular Formula
C38H56N6O10
Molecular Weight
756.89
References & Citations
[1]Zhang D, et al. Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules. J Med Chem. 2025 Jun 26;68 (12) :12641-12657.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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