HSP90i-COCH2CH2-PEG4-NHBoc

HSP90i-COCH2CH2-PEG4-NHBoc is a conjugate of the HSP90 Ligand (HY-174476) and the linker (HY-W021787) . HSP90i-COCH2CH2-PEG4-NHBoc can be used for synthesis of LYTACs, such as dPDL1-4 (HY-174468) [1].

Product Specifications

UNSPSC

12352005

Target

HSP

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

CC(C1=C(C=C(C(C2=NN=C(N2C3=CC=C(C=C3)CN4CCN(CC4)C(CCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O)O)=C1)O)O)C

Molecular Formula

C38H56N6O10

Molecular Weight

756.89

References & Citations

[1]Zhang D, et al. Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules. J Med Chem. 2025 Jun 26;68 (12) :12641-12657.