Azilsartan (medoxomil monopotassium) (Standard)

Azilsartan (medoxomil monopotassium) (Standard) is the analytical standard of Azilsartan (medoxomil monopotassium) . This product is intended for research and analytical applications. 0

Product Specifications

CAS Number

[863031-24-7]

UNSPSC

12352100

Target

Angiotensin Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Cardiovascular Disease; Endocrinology

Smiles

O=C(C1=C2C(N=C(OCC)N2CC3=CC=C(C4=CC=CC=C4C5=NC(O[N-]5)=O)C=C3)=CC=C1)OCC6=C(C)OC(O6)=O.[K+]

Molecular Formula

C30H23KN4O8

Molecular Weight

606.62

References & Citations

[1]Kajiya T, Ho C, Wang J, Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker. J Hypertens. 2011 Dec;29 (12) :2476-83.|[2]Kusumoto K, Igata H, Ojima M, Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models.|[3]Perry CM. Azilsartan medoxomil: a review of its use in hypertension. Clin Drug Investig. 2012 Sep 1;32 (9) :621-39.|[4]Pierini D, Anderson KV. Azilsartan medoxomil/chlorthalidone: a new fixed-dose combination antihypertensive. Ann Pharmacother. 2013 May;47 (5) :694-703.|[5]French CJ, et al. The angiotensin receptor blocker, azilsartan medoxomil (TAK-491), suppresses vascular wall expression of plasminogen activator inhibitor type-I protein potentially facilitating the stabilization of atherosclerotic plaques. J Cardiovasc Pharmacol. 2011 Aug;58 (2) :143-8. |[6]Ye Y, et al. Additive effect of TAK-491, a new angiotensin receptor blocker, and pioglitazone, in reducing myocardial infarct size. Cardiovasc Drugs Ther. 2010 Apr;24 (2) :107-20.