AChE/BChE-IN-28
AChE/BChE-IN-28 (Compound 5q) is a BChE inhibitor with an IC50 of 13.49 μM. AChE/BChE-IN-28 also exerts moderate inhibitory effect on AChE, with an IC50 of 35.23 μM. AChE/BChE-IN-28 can be used in the research of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(OC(C)(C)C)NC1CN(C(/C=C/C2=CC=C(OCC)C(OC)=C2)=O)CCC1
Molecular Formula
C22H32N2O5
Molecular Weight
404.50
References & Citations
[1]Esmkhani M, et al. Design and evaluation of substituted cinnamoyl piperidinyl acetate derivatives as potent cholinesterase inhibitors. Sci Rep. 2025 Jun 2;15 (1) :19346.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Curated Selection
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