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KMT9-IN-2

KMT9-IN-2 (Compound 7b) is an active form of a KMT9 inhibitor (Kd of 10 nM) . KMT9-IN-2 can be used in the research of colon cancer[1].

Product Specifications

UNSPSC

12352005

Target

Epigenetic Reader Domain

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

O[C@@H]1[C@H](O)[C@@H](CN(CC[C@@H](N)C(O)=O)CCCNCCC2=CC(F)=C(C=C2)OC3=CC=C(C=C3)Cl)C[C@H]1N4C=CC5=C(N=CN=C54)NC

Molecular Formula

C34H43ClFN7O5

Molecular Weight

684.20

References & Citations

[1]Wang S, et al. Structure-Guided Design of a KMT9 Inhibitor Prodrug with Cellular Activity. J Med Chem. 2025 Jul 10;68 (13) :13295-13320.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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