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HDAC6-IN-62

HDAC6-IN-62 (Compound 2.12) is a selective HDAC6 inhibitor, with an IC50 value of 0.25 nM. HDAC6-IN-62 can be used in the research of Charcot-Marie-Tooth disease[1].

Product Specifications

CAS Number

3056725-89-1

UNSPSC

12352005

Target

HDAC

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Neurological Disease

Smiles

O=C(C1=CC(F)=C(C=C1)CN2C3=C(C=CC4=C2N=CC=C4)C=CC=N3)NO

Molecular Formula

C20H15FN4O2

Molecular Weight

362.36

References & Citations

[1]Liang S H. Novel Heterocyclic 5 H-Dibenzo [b, f] azepine Derivatives as Selective HDAC6 Inhibitors for Treatment of Charcot Marie Tooth Disease. ACS Medicinal Chemistry Letters, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC6

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