HDAC6-IN-62

HDAC6-IN-62 (Compound 2.12) is a selective HDAC6 inhibitor, with an IC50 value of 0.25 nM. HDAC6-IN-62 can be used in the research of Charcot-Marie-Tooth disease[1].

Product Specifications

CAS Number

[3056725-89-1]

UNSPSC

12352005

Target

HDAC

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Neurological Disease

Smiles

O=C(C1=CC(F)=C(C=C1)CN2C3=C(C=CC4=C2N=CC=C4)C=CC=N3)NO

Molecular Formula

C20H15FN4O2

Molecular Weight

362.36

References & Citations

[1]Liang S H. Novel Heterocyclic 5 H-Dibenzo [b, f] azepine Derivatives as Selective HDAC6 Inhibitors for Treatment of Charcot Marie Tooth Disease. ACS Medicinal Chemistry Letters, 2025.