PSEC13

PSEC13 is an activator of HSF-1/DAF-16 axis. PSEC13 can upregulate heat shock proteins. PSEC13 can form hydrogen bonds with key residues in the HSP-16.2 active site. PSEC13 can be used to enhance proteostasis and extend lifespan through the modulation of HSP-16.2. PSEC13 could promote the nuclear translocation of daf-16, upgrading the proportion of intermediate. PSEC13 can be studied in research for aging and age-related diseases[1].

Product Specifications

UNSPSC

12352005

Target

HSP

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

COC1=C(O)C(OC)=CC([C@@H]2CC(OC3=C2C4=C(C[C@@H](OC(C5=CC(O)=C(O)C(O)=C5)=O)[C@@H](C6=CC(O)=C(O)C(O)=C6)O4)C(O)=C3)=O)=C1

Molecular Formula

C33H28O15

Molecular Weight

664.57

References & Citations

[1]Zi Yang, et al., (2025) . Undescribed Phenylpropanoid-Substituted Ester-Type Catechins from Green Tea Exert Antiaging Effects in Caenorhabditis elegans via Activating DAF-16, HSF-1, and Heat Shock Proteins. J. Agric. Food Chem. 2025, 73, 25, 15673–15692.