PAN endonuclease-IN-4

PAN endonuclease-IN-4 (Compound 41) is an inhibitor of PAN endonuclease with antiviral properties. PAN endonuclease-IN-4 is the prodrug of 39- (S) . PAN endonuclease-IN-4 can significantly suppress viral replication in an A/WSN/33 infected mouse model[1].

Product Specifications

UNSPSC

12352005

Target

Influenza Virus

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

CC(C)N(C1(COC1)N([C@@H]2C3=C(SCC4=C(C(F)=CC=C42)F)C=CC=C3)N5C=C6)C(C5=C(OCOC(OC)=O)C6=O)=O

Molecular Formula

C29H27F2N3O7S

Molecular Weight

599.60

References & Citations

[1]Shuangrong Liu, et al., (2025) . Design and Synthesis of PAN Endonuclease Inhibitors through Spirocyclization Strategy against Influenza A Virus. . Med. Chem. 2025, 68, 13, 13393–13407.