PAN endonuclease-IN-3
PAN endonuclease-IN-3 is a potent PAN endonuclease inhibitor that against influenza virus polymerase complexes with an IC50 of 17.4 nM. PAN endonuclease-IN-3 demonstrates potent inhibitory activities against PAN endonuclease. PAN endonuclease-IN-3 demonstrates robust antiviral activities against multiple current and different influenza virus strains while showing minimal cytotoxicity in MDCK cells. PAN endonuclease-IN-3 significantly suppresses viral replication in an A/WSN/33 infected mouse model[1].
Product Specifications
UNSPSC
12352005
Target
Endonuclease; Influenza Virus
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
CC(C)N(C1(COC1)N([C@@H]2C3=C(SCC4=C(C(F)=CC=C42)F)C=CC=C3)N5C=C6)C(C5=C(O)C6=O)=O
Molecular Formula
C26H23F2N3O4S
Molecular Weight
511.54
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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