Opioid receptor antagonist 2
Opioid receptor antagonist 2 (Compound 9) is a potent opioid receptor antagonist. Opioid receptor antagonist 2 can reverse ventilatory depression and vocal cord closure induced by fentanyl analogs in mice. Opioid receptor antagonist 2 is promising for research of acute poisoning such as respiratory depression caused by overdose of opioids[1].
Product Specifications
CAS Number
[676494-79-4]
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Smiles
NC(C1=CN=C(OC2=CC=C(CNCCC3=CC=CC=C3)C=C2)C=C1)=O
Molecular Formula
C21H21N3O2
Molecular Weight
347.41
References & Citations
[1]Martin J, et al. Searching for Synthetic Opioid Rescue Agents. 2: Identification of an Ultra-Potent Synthetic Opioid Rescue Agent. J Med Chem. 2025 Jun 26;68 (12) :13057-13074.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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