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Opioid receptor antagonist 2

Opioid receptor antagonist 2 (Compound 9) is a potent opioid receptor antagonist. Opioid receptor antagonist 2 can reverse ventilatory depression and vocal cord closure induced by fentanyl analogs in mice. Opioid receptor antagonist 2 is promising for research of acute poisoning such as respiratory depression caused by overdose of opioids[1].

Product Specifications

CAS Number

676494-79-4

UNSPSC

12352005

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Smiles

NC(C1=CN=C(OC2=CC=C(CNCCC3=CC=CC=C3)C=C2)C=C1)=O

Molecular Formula

C21H21N3O2

Molecular Weight

347.41

References & Citations

[1]Martin J, et al. Searching for Synthetic Opioid Rescue Agents. 2: Identification of an Ultra-Potent Synthetic Opioid Rescue Agent. J Med Chem. 2025 Jun 26;68 (12) :13057-13074.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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