TFSeB
TFSeB is an orally active neuroprotective agent. TFSeB can reduce Streptozotocin (STZ) (HY-13753) induced MAO-B and AChE activity. TFSeB exerts neuroprotective effects by increasing the expression of BCL-2, BDNF, NRF2, and decreasing the expression of BAX. TFSeB can reduce lipid peroxidation (TBARS) and reactive oxygen species (ROS) levels. TFSeB can reduce neuroinflammation. TFSeB can be used for research on Alzheimer’s disease[1].
Product Specifications
CAS Number
[3017240-62-6]
UNSPSC
12352005
Target
Bcl-2 Family; Cholinesterase (ChE) ; Monoamine Oxidase; NF-κB; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
FC(F)(C1=CC=CC([Se]CC2CC3=C(O2)C=CC=C3)=C1)F
Molecular Formula
C16H13F3OSe
Molecular Weight
357.23
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; Bax; Bcl-2
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