PLpro-IN-9
PLpro-IN-9 (Compound 14e) is a SARS-CoV-2 PLpro inhibitor with an IC50 of 12.0 μM and a KD of 1.86 μM. PLpro-IN-9 has low cytotoxicity but poor metabolic stability. PLpro-IN-9 can be used in the research of SARS-CoV-2[1].
Product Specifications
UNSPSC
12352100
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC1=CC(C2=CC(NS(=O)(C3=CC=CC=C3)=O)=CC=C2)=NN1)C(S4)=CC=C4C=O
Molecular Formula
C21H16N4O4S2
Molecular Weight
452.51
References & Citations
[1]Wu C, et al. Discovery of 3-phenyl-1H-5-pyrazolylamides as PLpro inhibitors through virtual screening and structure optimization. Bioorg Med Chem Lett. 2025 Jun 3;127:130293.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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