CYP51-IN-25
CYP51-IN-25 is a orally active broad spectrum antifungal agent with the MIC80 of 0.00625-0.05 μg/mL. is a CYP51-IN-25 is a deuterated compound with antibiotic properties. CYP51-IN-25 can inhibit the fungal CYP51 enzyme, block ergosterol synthesis, and disrupt cell membrane integrity. CYP51-IN-25 can be used for research on fungal infections[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450; Fungal; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
FC1=CC=C([C@]([C@H](C)N(C([2H])([2H])[2H])CC2=CC=C(C3=CC=C(OC(F)(F)F)C=C3)C=C2)(O)CN4C=NC=N4)C(F)=C1
Molecular Formula
C27H22D3F5N4O2
Molecular Weight
535.52
References & Citations
[1]Sun Y, et al. Design, Synthesis, and Biological Activity Evaluation of Deuterated Diphenyl Azole Alcohol-Based CYP51 Inhibitors. J Med Chem. 2025 Jun 12;68 (11) :12229-12257.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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