Gamhepathiopine
Gamhepathiopine is a thienopyrimidinone compound. Gamhepathiopine exerts antimalarial effects by targeting the Qo site of Plasmodium falciparum cytochrome b and inhibiting the activity of complex III in the electron transport chain[1].
Product Specifications
CAS Number
[1620442-30-9]
UNSPSC
12352005
Target
Mitochondrial Metabolism; Parasite
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
CC1=CC=C(C2=CC(N=C(NC(C)(C)C)NC3=O)=C3S2)C=C1
Molecular Formula
C17H19N3OS
Molecular Weight
313.42
References & Citations
[1]Wiedemar N, et al. The Thienopyrimidinone Gamhépathiopine Targets the QO Site of Plasmodium falciparum Cytochrome b. ACS Infect Dis. 2025 Jun 13;11 (6) :1719-1728.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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