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SDH-IN-29

SDH-IN-29 (Compound A33) is a SDH inhibitor with an IC50 of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC50s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively) . SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew[1].

Product Specifications

CAS Number

[3085095-22-0]

UNSPSC

12352005

Target

Fungal; Succinate Dehydrogenase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

N#CC(CC1=CC(Cl)=CC(OC(F)(F)F)=C1)C(C2=CN(C)N=C2C(F)F)=O

Molecular Formula

C16H11ClF5N3O2

Molecular Weight

407.72

References & Citations

[1] Cheng L, et al. Discovery of Novel Pyrazole β-Ketonitrile Derivatives as Broad Spectrum SDHI Fungicides by Introducing a Flexible Motif. J Agric Food Chem. 2025 Jun 18;73 (24) :14831-14838.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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