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Antifungal agent 134

Antifungal agent 134 (Compound B13) is an antifungal agent with EC50s of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL for Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata, respectively. Antifungal agent 134 can disrupt the cell membrane and mitochondria of the hyphae, leading to significant ROS accumulation. Antifungal agent 134 also has significant herbicidal activities against field weeds, such as Amaranthus retroflexus L and Abutilon theophrasti Medicus. Antifungal agent 134 can be used for crop diseases and field weeds research[1].

Product Specifications

CAS Number

[3080992-04-4]

UNSPSC

12352005

Target

Fungal; Herbicide; Reactive Oxygen Species (ROS)

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Infection

Smiles

O=C(NNC1=CC=C(F)C=C1)COC2=CC(O3)=C(C=C2)C(C(F)(F)F)=CC3=O

Molecular Formula

C18H12F4N2O4

Molecular Weight

396.29

References & Citations

[1]Li Y, et al. Discovery of Coumarin-7-N/O-Acethydrazide Derivatives as Novel Antifungal and Herbicidal Agents. J Agric Food Chem. 2025 Jun 18;73 (24) :14783-14795.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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