PDE3/4-IN-2
PDE3/4-IN-2 (Compound 1) is a PDE3/PDE4 dual-target inhibitor, with IC50 values of 0.13 nM and 50 nM against PDE3A and PDE4B1, respectively. PDE3/4-IN-2 can be used in the research of PDE-related diseases, such as asthma, obstructive pulmonary disease, sepsis, and nephritis[1].
Product Specifications
CAS Number
[2857007-03-3]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C1N=C(N(CCN2C(NCC2)=O)C3=C(C)C=C(C)C=C3C)C=C4C5=C(CCN14)C=C(OC)C(OC)=C5
Molecular Formula
C28H33N5O4
Molecular Weight
503.59
References & Citations
[1]Li ZY, et al. Isoquinolone compound and use thereof. WO2022228544A1. 2022-11-03.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE3; PDE4
Available Sizes
Curated Selection
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