Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mefloquine (Standard)

Mefloquine (Standard) is the analytical standard of Mefloquine. This product is intended for research and analytical applications. Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research[1][2][3].

Product Specifications

CAS Number

53230-10-7

UNSPSC

12352100

Target

Autophagy; Parasite; Potassium Channel; Reference Standards; ROS Kinase; SARS-CoV

Related Pathways

Anti-infection; Autophagy; Membrane Transporter/Ion Channel; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Smiles

O[C@H]([C@]1([H])NCCCC1)C2=CC(C(F)(F)F)=NC3=C(C(F)(F)F)C=CC=C32

Molecular Formula

C17H16F6N2O

Molecular Weight

378.31

References & Citations

[1]Kang J, et al. Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK andHERG. J Pharmacol Exp Ther. 2001 Oct;299 (1) :290-6.|[2]Yan KH, et al. Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling. Oncol Lett. 2013 May;5 (5) :1541-1545.|[3]Kaho Shionoya, et al. Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro. Front Microbiol. 2021 Apr 30;12:651403.|[4]Rafael Pacheco-Costa, et al. Reversal of loss of bone mass in old mice treated with mefloquine. Bone. 2018 Sep;114:22-31.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Apc2 (ANAPC2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3E1]
TA503573AM 100 µL

Apc2 (ANAPC2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3E1]

Sign In for Pricing
View Details
Kan Rabbit Polyclonal Antibody
AP55043SU-N 200 µL

Kan Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Perfluoro-n-pentane
TRC-P229715-5G 5 g

Perfluoro-n-pentane

Sign In for Pricing
View Details
LYVE1 (NM_006691) Human Over-expression Lysate
LY402008 100 µg

LYVE1 (NM_006691) Human Over-expression Lysate

Sign In for Pricing
View Details
OXGR1 Recombinant Rabbit Monoclonal Antibody [JE64-04]
HA721074 100 µL

OXGR1 Recombinant Rabbit Monoclonal Antibody [JE64-04]

Sign In for Pricing
View Details
alpha 2a Adrenergic Receptor (ADRA2A) (C-term) Rabbit Polyclonal Antibody
AP23299PU-N 100 µg

alpha 2a Adrenergic Receptor (ADRA2A) (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details