Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mefloquine (Standard)

Mefloquine (Standard) is the analytical standard of Mefloquine. This product is intended for research and analytical applications. Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research[1][2][3].

Product Specifications

CAS Number

53230-10-7

UNSPSC

12352100

Target

Autophagy; Parasite; Potassium Channel; Reference Standards; ROS Kinase; SARS-CoV

Related Pathways

Anti-infection; Autophagy; Membrane Transporter/Ion Channel; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Smiles

O[C@H]([C@]1([H])NCCCC1)C2=CC(C(F)(F)F)=NC3=C(C(F)(F)F)C=CC=C32

Molecular Formula

C17H16F6N2O

Molecular Weight

378.31

References & Citations

[1]Kang J, et al. Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK andHERG. J Pharmacol Exp Ther. 2001 Oct;299 (1) :290-6.|[2]Yan KH, et al. Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling. Oncol Lett. 2013 May;5 (5) :1541-1545.|[3]Kaho Shionoya, et al. Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro. Front Microbiol. 2021 Apr 30;12:651403.|[4]Rafael Pacheco-Costa, et al. Reversal of loss of bone mass in old mice treated with mefloquine. Bone. 2018 Sep;114:22-31.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ZNF33A (NM_001278170) Human Tagged ORF Clone
RG239624 10 µg

ZNF33A (NM_001278170) Human Tagged ORF Clone

Sign In for Pricing
View Details
Mouse IL-5 Recombinant Rabbit monoclonal Antibody
HA725035 100 µL

Mouse IL-5 Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
BAD (Ab-91/128) Antibody
8B0821-AAT 50 µg

BAD (Ab-91/128) Antibody

Sign In for Pricing
View Details
NUMB Antibody
KC-1440-01 50 μL

NUMB Antibody

Sign In for Pricing
View Details
NUMB Antibody
KC-1440-02 100 µL

NUMB Antibody

Sign In for Pricing
View Details
NUMB Antibody
KC-1440-03 1 mL

NUMB Antibody

Sign In for Pricing
View Details