SARS-CoV-2-IN-113
SARS-CoV-2-IN-113 (Compound 24) is a sulfonohydrazide derivative against SARS-CoV-2 infection with an IC50 of 8.320 μM. SARS-CoV-2-IN-113 exerts potent antiviral effects by inhibiting the entry and replication of SARS-CoV-2, and downregulating the expression of genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 has high selectivity and low cytotoxicity, and can be used in the research of SARS-CoV-2[1].
Product Specifications
CAS Number
[455304-63-9]
UNSPSC
12352100
Target
Angiotensin-converting Enzyme (ACE) ; SARS-CoV
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
CC1=CC=C(C=C1)S(=O)(N/N=C/C2=C(C(O)=C(C=C2)O)O)=O
Molecular Formula
C14H14N2O5S
Molecular Weight
322.34
References & Citations
[1]Khan Z, et al. Sulfonohydrazide as a potential inhibitor of SARS-CoV-2 infection. Sci Rep. 2025 May 28;15 (1) :18732.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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