MePT-S-N-Pme
MePT-S-N-Pme is an inhibitor of SARS-CoV-2 RdRp activity. MePT-S-N-Pme demonstrates a significant reduced reporter activity with an IC50 of 7 μM in HEK 293 cells. MePT-S-N-Pme has a slight inhibitory effect on nucleotidyltransferase activity. MePT-S-N-Pme significantly inhibits SARS-CoV-2 replication in vitro[1].
Product Specifications
CAS Number
852301-66-7
UNSPSC
12352100
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=CC=CC=C1N2N=NN=C2SC3=C(C=C(C=C3)C(C4=CC=CC=C4)=O)[N+]([O-])=O
Molecular Formula
C21H15N5O3S
Molecular Weight
417.44
References & Citations
[1]Kang, E., et al., (2025) . Construction and validation of a cell based reporter assay for identifying inhibitors of SARS coronavirus 2 RNA dependent RNA polymerase activity. Scientific reports, 15 (1), 18443.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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