HPK1 ligand 3-dimethylph tetrahydropyridine
HPK1 ligand 3-dimethylph tetrahydropyridine is a Target Protein Ligand-Linker Conjugate. HPK1 ligand 3-dimethylph tetrahydropyridine can be used to synthesize PROTAC HPK1 Degrader-4 (HY-174135) [1].
Product Specifications
UNSPSC
12352005
Target
Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
CC(C=C(C=C1C)C2=NC3=C(N=C2)NC=C3C4=CC(C)=C(C=C4)C(N(C)C)=O)=C1C5=CCNCC5
Molecular Formula
C29H31N5O
Molecular Weight
465.59
References & Citations
[1]Wu M, et al. Discovery of a New and Selective HPK1 PROTAC for Enhancing Tumor Immunotherapy through Eliminating GLK Degradation. J Med Chem. 2025 Jun 12;68 (11) :10800-10822.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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