CYP51-IN-23-d3
CYP51-IN-23-d3 is a potent and broad-spectrum CYP51 inhibitor with a MIC80 of 1 μg/mL against Aspergillus fumigatum. CYP51-IN-23-d3 can prevent fungal phase transformation and biofilm formation. CYP51-IN-23-d3 exhibits anti-drug resistance activity and fungal activity, and shows excellent safety for cells and significant pharmacological activity in mice. CYP51-IN-23-d3 can be used for the study of invasive fungal infections (IFIs) [1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450; Fungal; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
FC1=CC(F)=CC=C1C(CN(C([2H])([2H])[2H])CC2=CC=C(N3CCN(C(C4=CC(Br)=CC=C4)=O)CC3)C=C2)(O)CN5C=NN=N5
Molecular Formula
C29H27D3BrF2N7O2
Molecular Weight
629.51
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
CYP51
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