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TERT ligand-1

TERT ligand-1 is a PROTAC target protein ligand that can be used to synthesize the PROTAC NU-PRO-1. NU-PRO-1 induces TERT degradation in cancer cells[1].

Product Specifications

CAS Number

2412120-47-7

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; Telomerase

Related Pathways

Cell Cycle/DNA Damage; PROTAC

Field of Research

Cancer

Smiles

O=C([C@](C1=O)(C)[C@H](CCC2=CN(CC3=CC=C(F)C=C3F)N=N2)O[C@H](C)C1=C)OC

Molecular Formula

C21H23F2N3O4

Molecular Weight

419.42

References & Citations

[1]Frost GB, et al. Telomerase reverse transcriptase degradation via a rationally designed covalent proteolysis targeting chimera. Bioorg Med Chem Lett. 2025 Sep 1;125-126:130286.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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