TRPV1 agonist-1
TRPV1 agonist-1 (Compound 13) is an orally active non-irritating TRPV1 agonist with EC50 values of 4.5 and 0.57 nM for human and rat. TRPV1 agonist-1 can improve swallowing function in rats. TRPV1 agonist-1 can be used in the research of dysphagia[1].
Product Specifications
CAS Number
[2763372-26-3]
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Smiles
COC(C=C1CC(NC2=CC=CC([C@H]3CC[C@H](CC3)OC(C4CCCCC4)=O)=C2)=O)=C(C=C1)O
Molecular Formula
C28H35NO5
Molecular Weight
465.58
References & Citations
[1]Kitano H, et al. Discovery of nonpungent Transient Receptor Potential Vanilloid (TRPV1) agonist antedrugs for treatment of dysphagia. Bioorg Med Chem Lett. 2025 Sep 1;125-126:130287.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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