Nurr1 agonist 13

Nurr1 agonist 13 (Compound 1) is a potent nuclear receptor related 1 (Nurr1, NR4A2) agonist with an EC50 value of 0.06 μM. Nurr1 agonist 13 is promising for research of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis[1].

Product Specifications

UNSPSC

12352005

Target

Nuclear Hormone Receptor 4A/NR4A

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Neurological Disease

Smiles

FC1=CC(C(C=CC=C2)=C2OCC3=CC=CC=C3)=CC=C1NC(C4=C(C(O)=O)CCC4)=O

Molecular Formula

C26H22FNO4

Molecular Weight

431.46

References & Citations

[1]López-García Ú, et al. Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design[J]. Communications Chemistry, 2025, 8 (1) : 1-11.