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SEH-IN-3

SEH-IN-3 (Compound 50) is a soluble epoxide hydrolase (sEH) inhibitor (IC50: 0.46 nM) . sEH-IN-3 can maintain the anti-inflammatory and analgesic activities of epoxyeicosatrienoic acids (EETs) [1].

Product Specifications

UNSPSC

12352100

Target

Epoxide Hydrolase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C(C1=CN=C(N2CCN(CC3=CC=CC(Cl)=C3)C2=O)S1)NCC4=CC=C(OC)C=C4C(F)(F)F

Molecular Formula

C23H20ClF3N4O3S

Molecular Weight

524.94

References & Citations

[1]Lengerli D, et al. Potent soluble epoxide hydrolase inhibitors based on thiazole-5-carboxamide structure with imidazolidinone moiety as a secondary pharmacophore. Bioorg Chem. 2025 May 29;163:108644.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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