SEH-IN-3
SEH-IN-3 (Compound 50) is a soluble epoxide hydrolase (sEH) inhibitor (IC50: 0.46 nM) . sEH-IN-3 can maintain the anti-inflammatory and analgesic activities of epoxyeicosatrienoic acids (EETs) [1].
Product Specifications
UNSPSC
12352100
Target
Epoxide Hydrolase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(C1=CN=C(N2CCN(CC3=CC=CC(Cl)=C3)C2=O)S1)NCC4=CC=C(OC)C=C4C(F)(F)F
Molecular Formula
C23H20ClF3N4O3S
Molecular Weight
524.94
References & Citations
[1]Lengerli D, et al. Potent soluble epoxide hydrolase inhibitors based on thiazole-5-carboxamide structure with imidazolidinone moiety as a secondary pharmacophore. Bioorg Chem. 2025 May 29;163:108644.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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