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SARS-CoV-2-IN-112

SARS-CoV-2-IN-112 (Compound 6f) is an orally active and non-peptidic SARS-CoV-2 main protease inhibitor with an IC50 of 6.48 μM. SARS-CoV-2-IN-11 has potent antiviral activity with low cytotoxicity against WI-38 cells (IC50: 53.81 μM) . SARS-CoV-2-IN-112 can be used for coronaviruses COVID-19 research[1].

Product Specifications

UNSPSC

12352100

Target

SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

ClC1=CC=C(C=C1)NC(NNC(C2=CC=C(C=C2)NS(=O)(C3=CC=C(C=C3)OC)=O)=O)=S

Molecular Formula

C21H19ClN4O4S2

Molecular Weight

490.98

References & Citations

[1]El-Sayed SM, et al. Tipranavir analogs as antiviral agents: Design, synthesis, in vitro, and in silico study of new SARS-CoV-2 main protease inhibitors. Bioorg Chem. 2025 May 23;163:108624.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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