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NARS-3′

NARS-3′ is an orally active reversible xanthine oxidase (XO) inhibitor with the IC50 of 21.01 μM. NARS-3′ can competitively inhibit XO activity and reduce uric acid production. NARS-3′ can reduce renal damage in hyperuricemia mice. NARS-3′ can be used for the study of hyperuricemia[1].

Product Specifications

CAS Number

[2702589-46-4]

UNSPSC

12352100

Target

Xanthine Oxidase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C1CC(OC2=CC(O)=CC(O)=C12)C3=CC(S(=O)(O[Na])=O)=C(C=C3)O

Molecular Formula

C15H11NaO8S

Molecular Weight

374.30

References & Citations

[1]Luo Y, et al. Xanthine oxidase inhibitory and anti-hyperuricemic properties of sulfonate derivatives of naringenin. Bioorg Chem. 2025 May 20;163:108618.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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