NARS-3′
NARS-3′ is an orally active reversible xanthine oxidase (XO) inhibitor with the IC50 of 21.01 μM. NARS-3′ can competitively inhibit XO activity and reduce uric acid production. NARS-3′ can reduce renal damage in hyperuricemia mice. NARS-3′ can be used for the study of hyperuricemia[1].
Product Specifications
CAS Number
2702589-46-4
UNSPSC
12352100
Target
Xanthine Oxidase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C1CC(OC2=CC(O)=CC(O)=C12)C3=CC(S(=O)(O[Na])=O)=C(C=C3)O
Molecular Formula
C15H11NaO8S
Molecular Weight
374.30
References & Citations
[1]Luo Y, et al. Xanthine oxidase inhibitory and anti-hyperuricemic properties of sulfonate derivatives of naringenin. Bioorg Chem. 2025 May 20;163:108618.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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