Thalidomide (methylamino) acetaldehyde

Thalidomide (methylamino) acetaldehyde is an E3 ubiquitinase ligand-linker conjugate. Thalidomide (methylamino) acetaldehyde can be used to synthesize WZH-17-002 (HY-174315) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(N(CC1)CCN1C(CC2)CCN2C(C(CC)=C3)=CC(OC)=C3NC(N=C4NC5=CC=C6OCCOC6=C5N(S(C)(=O)=O)C)=NC=C4Br)CNC

Molecular Formula

C35H48BrN9O6S

Molecular Weight

802.78

References & Citations

[1]Gao F, et al. Discovery of an ALK degrader for lorlatinib-resistant compound mutations. Eur J Med Chem. 2025 Oct 15;296:117835.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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