Thalidomide (methylamino) acetaldehyde
Thalidomide (methylamino) acetaldehyde is an E3 ubiquitinase ligand-linker conjugate. Thalidomide (methylamino) acetaldehyde can be used to synthesize WZH-17-002 (HY-174315) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(N(CC1)CCN1C(CC2)CCN2C(C(CC)=C3)=CC(OC)=C3NC(N=C4NC5=CC=C6OCCOC6=C5N(S(C)(=O)=O)C)=NC=C4Br)CNC
Molecular Formula
C35H48BrN9O6S
Molecular Weight
802.78
References & Citations
[1]Gao F, et al. Discovery of an ALK degrader for lorlatinib-resistant compound mutations. Eur J Med Chem. 2025 Oct 15;296:117835.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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