NAPAP
NAPAP is a thrombin inhibitor. It has potent antithrombin activity (Ki: 2.1 nM) . NAPAP selectively inhibits thrombin via a rapid binding mechanism, and has weaker inhibitory effects on trypsin, factor Xa, and plasmin. NAPAP can be used in the study of thrombotic diseases (e.g., venous thrombosis, myocardial infarction) [1].
Product Specifications
CAS Number
[137171-40-5]
UNSPSC
12352005
Target
Thrombin
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
N=C(N)C(C=C1)=CC=C1C[C@H](C(N2CCCCC2)=O)NC(CNS(=O)(C3=CC4=C(C=CC=C4)C=C3)=O)=O
Molecular Formula
C27H31N5O4S
Molecular Weight
521.63
References & Citations
[1]Steinmetzer T, et al. Structure-activity relationships of new NAPAP-analogs. J Enzyme Inhib. 2001;16 (3) :241-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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