RDS-04-010

RDS-04-010 is an atypical dopamine transporter (DAT) inhibitor. RDS-04-010 has the effect of inhibiting cocaine intake and seeking behavior. RDS-04-010 exerts its modulatory effect mainly by binding to the inward conformation of DAT, thereby reducing the reinforcing effect of cocaine. RDS-04-010 can be used in the study of cocaine use disorder (CUD) [1].

Product Specifications

CAS Number

[2324109-06-8]

UNSPSC

12352005

Target

Dopamine Transporter

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Purity

98.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(C=C1)=CC=C1C(S(CCN2C[C@H](C)N(CC(C)O)[C@H](C)C2)=O)C3=CC=C(F)C=C3

Molecular Formula

C24H32F2N2O2S

Molecular Weight

450.58

References & Citations

[1]Soler-Cedeno O, et al. RDS-04-010: a novel atypical DAT inhibitor that inhibits cocaine taking and seeking and itself has low abuse potential in experimental animals. Transl Psychiatry. 2025 May 24;15 (1) :182.