PPARδ agonist 12

PPARδ agonist 12 (compound 25) is a PPARδ agonist that inhibits the production of inflammatory factors and nitric oxide. PPARδ agonist 12 can also effectively prevent macrophages from infiltrating inflammatory sites and can be used in inflammation research[1].

Product Specifications

CAS Number

[2982696-34-2]

UNSPSC

12352005

Target

NO Synthase; PPAR

Related Pathways

Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology

Smiles

O=C(COC1=CC=C(C=C1C)SCC2=NN=C(C3=CC=C(OC(F)(F)F)C=C3)S2)O

Molecular Formula

C19H15F3N2O4S2

Molecular Weight

456.46

References & Citations

[1]Preparation of thiadiazole compound for preventing or treating inflammatory diseases. World Intellectual Property Organization, WO2023177146 A1. 2023-09-21.