Antitumor agent-203
Antitumor agent-203 (compound 26) is a derivative of Exatecan (DX-8951) and can be used to prepare antibody-drug conjugates (ADCs), as the ADC Cytotoxin[1].
Product Specifications
CAS Number
2577204-44-3
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.07
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@H](O)C(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O
Molecular Formula
C27H26FN3O6
Molecular Weight
507.51
References & Citations
[1]Zhu Yi, et al. Preparation of exatecan derivatives and exatecan antibody conjugates useful for the treatment of cancer. China, CN111689980 A. 2020-09-22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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