Famciclovir-d6

Famciclovir-d6 (BRL 42810-d6) is deuterium labeled Famciclovir. Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection[1].

Product Specifications

CAS Number

[2587293-47-6]

Product Name Alternative

BRL 42810-d6

UNSPSC

12352005

Target

HBV; HSV; Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

NC1=NC=C2N=CN(CCC(COC(C([2H])([2H])[2H])=O)COC(C([2H])([2H])[2H])=O)C2=N1

Molecular Formula

C14H13D6N5O4

Molecular Weight

327.37

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Wutzler P, Ulbricht A, Färber I. Antiviral efficacies of famciclovir, valaciclovir, and brivudin in disseminated herpes simplex virus type 1 infection in mice. Intervirology. 1997;40 (1) :15-21.|[3]administration are replication defective. Hepatology. 1998 Feb;27 (2) :628-33. |[4]Harrell AW, et al. Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes. Drug Metab Dispos. 1993 Jan-Feb;21 (1) :18-23.