HIV Capsid-IN-2
HIV Capsid-IN-2 (Compound IC-2b4) is a potent HIV-1 capsid protein (CA) inhibitor. HIV Capsid-IN-2 shows inhibitory effects against both HIV-1 (EC50=0.08 μM) and HIV-2. HIV Capsid-IN-2 exerts inhibitory effects during both early and late stages of infection by directly and stably binding to HIV-1 CA[1].
Product Specifications
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N(C1=CC=C(OC)C=C1)C)[C@@H](NC(CN2C(CN(S(=O)(C3=CC=C(N)C=C3F)=O)CC2)=O)=O)CC4=CC(F)=CC(F)=C4
Molecular Formula
C29H30F3N5O6S
Molecular Weight
633.64
References & Citations
[1]Shi D, et al. Design, synthesis and structure-activity relationships of novel HIV capsid inhibitors with potent antiviral activities. Eur J Med Chem. 2025 May 22;295:117784.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1; HIV-2
Curated Selection
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