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FGFR-IN-21

FGFR-IN-21 (Compound FP1) is a selective covalent FGFR4 inhibitor with an IC50 value of 70 nM. FGFR-IN-21 is promising for research of FGFR signaling pathways in cancers[1].

Product Specifications

UNSPSC

12352005

Target

FGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

C=CC(NC1=CC=C(CN(C2=NC(NC3=CC=C(N4CCN(CCC#C)CC4)C=C3)=NC=C2CN5C6=CC(OC)=CC(OC)=C6)C5=O)C=C1)=O

Molecular Formula

C38H40N8O4

Molecular Weight

672.78

References & Citations

[1]Zhu D, et al. Design, synthesis and biological evaluation of the activity-based probes for FGFR covalent inhibitor. Eur J Med Chem. 2025 May 22;295:117795.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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