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PaFabV-IN-1

PaFabV-IN-1 (Compound 3e) is a selective Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (PaFabV) inhibitor with an IC50 value of 0.25 μM. PaFabV-IN-1 is promising for research of infections caused by P. aeruginosa and other Gram-negative bacteria[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OC1=C(OC2=CC=C(S(N(C)C)(=O)=O)C=C2)C=CC(CCCCC)=C1

Molecular Formula

C19H25NO4S

Molecular Weight

363.47

References & Citations

[1]Bulai R G, et al. Investigating the Structure-Activity-Relationship of Diaryl Ether-Based as paFabV Inhibitors: A Path to Novel Antibacterials[J]. European Journal of Medicinal Chemistry, 2025: 117782.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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