PaFabV-IN-1
PaFabV-IN-1 (Compound 3e) is a selective Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (PaFabV) inhibitor with an IC50 value of 0.25 μM. PaFabV-IN-1 is promising for research of infections caused by P. aeruginosa and other Gram-negative bacteria[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC1=C(OC2=CC=C(S(N(C)C)(=O)=O)C=C2)C=CC(CCCCC)=C1
Molecular Formula
C19H25NO4S
Molecular Weight
363.47
References & Citations
[1]Bulai R G, et al. Investigating the Structure-Activity-Relationship of Diaryl Ether-Based as paFabV Inhibitors: A Path to Novel Antibacterials[J]. European Journal of Medicinal Chemistry, 2025: 117782.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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