GRL-098-22
GRL-098-22 (Compound 6t) is a potent inhibitor targeting G protein-coupled receptor kinase 5 (GRK5) and GRK6 with IC50 values of 0.6 μM and 0.19 μM, respectively. GRL-098-22 is promising for research of diseases such as heart failure and multiple myeloma[1].
Product Specifications
UNSPSC
12352005
Target
G Protein-coupled Receptor Kinase (GRK)
Related Pathways
GPCR/G Protein
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C(N1C[C@@H](C(NC2=C(C)NC(/C=C3C(NC4=C\3C=C(C(N[C@@H](C5=CC=C(F)C=C5)C)=O)C=C4)=O)=C2C)=O)NCC1)OC(C)(C)C
Molecular Formula
C34H39FN6O5
Molecular Weight
630.71
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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