PTP1B-IN-31
PTP1B-IN-31 (Compound (S, S) -3ak) is a PTP1B inhibitor with an IC50 of 0.81 μM. PTP1B-IN-31 can inhibit the growth of tumor cells in synergy with the cytokine IFNγ. PTP1B-IN-31 can be used in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C1O[C@H](C=C1C2=CC=C3C(C=CC=C3)=C2)[C@@]4(C5=C(CCC=C5N(CC6=CC=CC=C6)C4=O)Br)O
Molecular Formula
C29H22BrNO4
Molecular Weight
528.39
References & Citations
[1]Shi T, et al. Multicatalysis-Enabled Multicomponent Reactions Generate a PTP1B Inhibitor. ACS Cent Sci. 2025 May 19;11 (6) :938-949.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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