CRBN ligand-186
CRBN ligand-186 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC[1].
Product Specifications
CAS Number
[3084710-09-5]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
N#CC(C(NS(=O)(N(CC)C)=O)=CC=C1F)=C1OC(C=C2C3=O)=CC=C2N=CN3[C@@H]4COC5(C4)CCN(CC5)C(CN6CCC(CC6)C7=CC=C(C=C7OS(=O)(F)=O)C8CCC(NC8=O)=O)=O
Molecular Formula
C44H48F2N8O11S2
Molecular Weight
967.03
References & Citations
[1]Kimberly Muno HILBY, et al. Covalent cereblon ligands. WO2025096856A1. 2025-05-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
