RET-IN-30
RET-IN-30 (Compound 28) is a RET inhibitor that exhibits inhibitory activity against both wild-type RET and some of its mutants. RET-IN-30 can inhibit the proliferation of A549 cells and has anti-tumor activity[1].
Product Specifications
CAS Number
[3081389-07-0]
UNSPSC
12352005
Target
RET
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
FC1=CC(OC2CN(C2)C3=NC=C(C=C3)C4=C5N=CC=NC5=CC(N(CC)CC)=C4)=CC=C1
Molecular Formula
C26H26FN5O
Molecular Weight
443.52
References & Citations
[1]LEE, et al. Novel quinoxaline compounds, manufacturing method thereof, and uses thereof. WO2025084787A1. 2025-04-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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